In what was meant as a harmless birthday prank, three of Reagan High School's most popular girls, Julie, Marcie, and Courtney pretend to kidnap their friend, the latter shoving a jawbreaker into the victim's mouth to keep her from screaming. Their plan goes awry when the girl accidentally swallows the jawbreaker, choking to death. The cool and calculating Courtney tries to cover the crime but is found out by school geek Fern Mayo. In return for her silence, Courtney transforms the gawky Fern into the stylishly beautiful Vylette, leaving the conscience-stricken Julie out in the cold, threatening to set her up for the girl's murder if she breaks her silence.

In the afterlife, one guardian helps a man through his trials, while his two colleagues help a former guardian on earth.

A dog looks to discover his purpose in life over the course of several lifetimes and owners.

The events in this movie take place around the same time as the events in The Bourne Ultimatum (2007). When a British reporter was writing an expose about Black Ops operations Treadstone and Black Briar, and the ones responsible for them are concerned. And when Jason Bourne, former Treadstone operative got the file on Treadstone and Black Briar and gave it to Pamela Landy who then passed it to the media. When the men behind Treadstone and Black Briar learn of this, they're concerned how this will affect other ops they have. They decide it's best to shut down all ops and make sure make everyone involved disappears. They try to take out Aaron Cross who is part of another op called Outcome, but he manages to survive. He then seeks out Dr. Marta Shearing who worked on him when he began. It seems part of the program is for all subjects to take medications but he has run out, which is why he seeks her. But someone tries to kill her. He saves her and she tells him, he should have stopped ...