Hunky NY lawyer Jeff Daly finally got engaged to fickle Sarah Huttinger, who presents him to her Pasadena family, who all soon take to him, for her sister's wedding to Scott. But Jeff's clever counting makes Sarah realize her dad Earl isn't her biological father. Once movie clues from family indicate as suspect successful author Beau Burroughs, she insists on meeting him. Only like her mother and grandmother, she has a one night-stand with Beau, which may well cost her Jeff.

Under the mistaken impression that his pet hamster, Abu, is ill Harry Hill and his Nan (Julie Walters) take him to the vet, who wrongly gives them the tragic news that Abu has one week to live. Harry, who thinks he speaks fluent hamster (but, in fact, misunderstands every squeak that comes out of his little pal's mouth), incorrectly thinks Abu's dying wish is a trip to Blackpool. With Nan making three, the trio embark on a road trip to the seaside town. Unbeknownst to them, the Vet is actually the dirty rotten henchman of Harry's evil twin brother Otto (Matt Lucas), who was raised separately by Alsatians. Addicted to Hula-Hoops and fueled by revenge, Otto's nefarious plot is to kidnap Abu and make him the centerpiece of the plastinated hamster world he's creating in his evil lair. Can Harry and Nan stop Otto before it's too late?

After retrieving the philosopher's stone at an auction but losing his girlfriend, The Librarian Flynn Carsen has a breakdown. Charlene and Judson ask him to spend some time on vacation. Flynn travels to New Orleans and he has a crush on a French singer (Simone Renoir). However he discloses that she is the guardian of a key to access the Judas Chalice that is capable to resurrect vampires. Meanwhile the former Russian Minister of Defense Sergei Kubichek is seeking the chalice to revive Vlad the vampire with the support of Professor Lazlo. Also to raise an army of undead to bring Russia back to the top of the world. When Simone reveals that she is a vampire, Flynn question whether she is not using him to reach the chalice and increase her power.

After the death of their grandfather Johann von Wolfhause, the brothers Jan and Todd Wolfhouse travel to Munich to fulfill a family tradition, spreading the ashes of Johann during the Oktoberfest. Their contact brings them to a secret beer competition, the Beerfest", where they are offended by Baron Wolfgang von Wolfhausen and the German branch of their family that accuse their great-grandmother of being a prostitute and their grandfather of stealing an old recipe of the best beer in Germany. Jan and Todd returns to USA humiliated and decide to organize a beer team to dispute the next Beerfest. They join Landfill, Barry and Fink and train long the year to participate in the competition. When they find the lost recipe hidden in a dummy, they feel that their German relatives told the truth. But the team is ready for the tough dispute.